Pick the word with the correct spelling.

The word with the correct spelling is Disease.

"Disease" refers to a disorder of structure or function in a human, animal, or plant, especially one that produces specific signs or symptoms. This is the standard and correct spelling of the word in English.

The other options ("Dicease," "Desease," and "Discease") are all common misspellings of this term.

Hence, the correct answer is Option 4 - Disease.